Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11385152 | 0.87 | HPGD (0.71) | HPGDGLARECQLNPSR1KMT2A | |
| SCHEMBL27399561 | 0.82 | HPGD (0.54) | HPGDGLARECQLNPSR1KMT2A | |
| SCHEMBL9152199 | 0.81 | CTSA (0.52) | NPSR1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL5685200 | 0.81 | HPGD (0.57) | HPGDGLARECQLNPSR1KMT2A | |
| SCHEMBL30530340 | 0.74 | TRPM8 (0.68) | HPGDGLARECQLNPSR1KMT2A | |
| SCHEMBL3637064 | 0.73 | ACP3 (0.49) | NPSR1HTTGAATDP1MAPT | |
| SCHEMBL9413681 | 0.72 | BRD4 (0.44) | HPGDNPSR1KMT2AMEN1ALDH1A1 | |
| M-Xylene SCHEMBL29227733 | 0.72 | HPGD (0.62) | HPGDKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL8921884 | 0.72 | ACP3 (0.49) | HTTGAAMAPTBRD4LMNA | |
| SCHEMBL12158735 | 0.72 | MGAM (0.58) | HPGDNPSR1KMT2AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414008-A | Hypotensive and antiatherosclerotic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |
| EP-0578002-A1 | Imidazolyl substituted phenylpropionic and cinnamic acid derivatives | BAYER AG (DE) | 1994-01-12 | — | — | EP | disclosed |