Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11385152 | 0.84 | HPGD (0.71) | HPGDGLARECQLL3MBTL1NPSR1 | |
| SCHEMBL9154048 | 0.82 | HPGD (0.58) | HPGDGLARECQLL3MBTL1NPSR1 | |
| SCHEMBL27534942 | 0.81 | GABBR2 (0.50) | KMT2ATSHRCYP2D6LMNASMN1; SMN2 | |
| SCHEMBL5685200 | 0.77 | HPGD (0.57) | HPGDGLARECQLL3MBTL1NPSR1 | |
| SCHEMBL27372093 | 0.75 | SLC7A5 (0.41) | KMT2AALDH1A1MAPTTSHRTACR1 | |
| SCHEMBL30530340 | 0.71 | TRPM8 (0.68) | HPGDGLARECQLL3MBTL1NPSR1 | |
| SCHEMBL1666938 | 0.71 | AKR1C3 (0.47) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL27640013 | 0.70 | PTGS2 (0.54) | HPGDRECQLALDH1A1MAPTLTB4R | |
| SCHEMBL28229181 | 0.70 | CYP2D6 (0.44) | KMT2AMEN1ALDH1A1TSHRCYP2D6 | |
| SCHEMBL28225086 | 0.70 | MMP8 (0.48) | L3MBTL1KMT2AMEN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1082041-A | The phenylpropionic acid of imidazolyl-replacement and cinnamic acid derivative | BAYER AG (DE) | 1994-02-16 | — | — | CN | disclosed |