Acrylic Acid

Acrylic Acid

SCHEMBL9155014

C=CC(=O)O.C=COC(C)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL8822896 0.89 THRB (0.32) THRB
SCHEMBL9483747 0.88
SCHEMBL6693176 0.88
Acrylic Acid SCHEMBL9154994 0.86 THRB (0.31) THRB
SCHEMBL4258778 0.86
SCHEMBL17417862 0.80
Acrylic Acid SCHEMBL28499334 0.80 THRB (0.38) THRBLMNA
SCHEMBL7899865 0.77 TSHR (0.35) THRB
SCHEMBL2196991 0.77 TSHR (0.35) THRB
SCHEMBL4893018 0.77 TSHR (0.35) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0448978-B1 Material for contact lenses and contact lenses prepared therefrom HOYA CORP (JP) 1995-02-01 EP disclosed
EP-0448978-A2 Material for contact lenses and contact lenses prepared therefrom HOYA CORPORATION (JP) 1991-10-02 EP disclosed