Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150777 | 0.93 | SMN1; SMN2 (0.45) | NPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL6940744 | 0.90 | NPC1 (0.42) | NPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL9158313 | 0.89 | — | — | |
| SCHEMBL9153940 | 0.86 | MAOB (0.43) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9140427 | 0.86 | NPC1 (0.45) | NPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL9142828 | 0.86 | NPC1 (0.47) | NPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL9307949 | 0.84 | TP53 (0.39) | NPC1RAB9A | |
| SCHEMBL9154452 | 0.84 | RECQL (0.46) | NPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL9307402 | 0.84 | PKM (0.47) | NPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL9307958 | 0.82 | TP53 (0.39) | NPC1RAB9AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514546-B1 | CHROMENE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-01-04 | — | — | EP | claimed |
| EP-0514546-A1 | CHROMENE DERIVATIVES, THEIR PRODUCTION AND USE. | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1992-11-25 | — | — | EP | claimed |
| WO-1991012249-A1 | CHROMENE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-22 | — | — | WO | claimed |