SCHEMBL9155146

SCHEMBL9155146

Cc1c(Br)c(O)c(Br)c(C)c1C(C)(C)c1c(C)c(Br)c(O)c(Br)c1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
HPGD P15428 3/20 0.38
ALOX15 P16050 3/20 0.38
HIF1A Q16665 3/20 0.38
HSD17B10 Q99714 3/20 0.38
RECQL P46063 3/20 0.38
MAPK1 P28482 1/20 0.38
CYP3A4 P08684 2/20 0.38
ALOX12 P18054 2/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
TSHR P16473 1/20 0.36
CASP1 P29466 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL299674 0.78 ALOX15 (0.50) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL298177 0.75 ALOX5 (0.32) ALDH1A1POLBCA2
SCHEMBL13964596 0.74 ALDH1A1 (0.50) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL6377646 0.74 ALDH1A1 (0.50) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL9503901 0.71 ALDH1A1 (0.47) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL11682268 0.70 CA1 (0.53) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL6115897 0.70 ALDH1A1 (0.62) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL13964610 0.69 ALDH1A1 (0.48) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL3418208 0.69 ALDH1A1 (0.62) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL13964612 0.67 ALDH1A1 (0.52) ALDH1A1HPGDALOX15HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0364785-B1 Thermosetting resin composition, printed circuit board using the resin composition and process for producing printed circuit board HITACHI LTD (JP) 1995-03-01 EP claimed
EP-0364785-B1 Thermosetting resin composition, printed circuit board using the resin composition and process for producing printed circuit board HITACHI LTD (JP) 1995-03-01 EP disclosed
US-5045381-A Containing (iso)cyanate compound and poly(p-hydroxystyrene) derivative HITACHI, LTD. (JP) 1991-09-03 US disclosed
EP-0364785-A1 Thermosetting resin composition, printed circuit board using the resin composition and process for producing printed circuit board HITACHI, LTD. (JP) 1990-04-25 EP disclosed
EP-0016057-B1 OPTICALLY TRANSPARENT, RADIOGRAPHICALLY OPAQUE TUBING GENERAL ELECTRIC COMPANY (US) 1983-06-22 EP disclosed
EP-0016057-A4 OPTICALLY TRANSPARENT, RADIOGRAPHICALLY OPAQUE TUBING. GEN ELECTRIC (US) 1980-11-14 EP disclosed
EP-0016057-A1 OPTICALLY TRANSPARENT, RADIOGRAPHICALLY OPAQUE TUBING. GEN ELECTRIC (US) 1980-10-01 EP disclosed
WO-1980000061-A1 OPTICALLY TRANSPARENT,RADIOGRAPHICALLY OPAQUE TUBING GEN ELECTRIC (US) 1980-01-24 WO disclosed
US-4182787-A Optically transparent, radiographically opaque tubing GENERAL ELECTRIC COMPANY (US) 1980-01-08 US disclosed