SCHEMBL915166

SCHEMBL915166

CCNC(=O)C[Si](OC)(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.40
FAAH O00519 1/20 0.39
ALDH1A1 P00352 1/20 0.34
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
KDM4E B2RXH2 2/20 0.33
RAB9A P51151 3/20 0.33
HPGD P15428 1/20 0.33
NPC1 O15118 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KMT2A Q03164 2/20 0.32
RXFP1 Q9HBX9 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
LMNA P02545 2/20 0.32
KDM4A O75164 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5666556 0.83 MCL1 (0.44) MCL1FAAHMMP1MMP2MMP3
SCHEMBL915521 0.80 MCL1 (0.39) MCL1FAAHALDH1A1MMP1MMP2
SCHEMBL10946037 0.78 ALDH1A1 (0.38) MCL1ALDH1A1SMN1; SMN2LMNAMAPT
SCHEMBL964969 0.74 CTSD (0.41) ALDH1A1KDM4EKMT2ALMNAKDM4A
SCHEMBL14084816 0.74 FAAH (0.60) FAAH
SCHEMBL13930299 0.73 MCL1 (0.44) MCL1FAAHALDH1A1MMP1MMP2
SCHEMBL10524685 0.73 MCL1 (0.44) MCL1FAAHALDH1A1MMP1MMP2
SCHEMBL8677830 0.73 MCL1 (0.44) MCL1FAAHALDH1A1MMP1MMP2
SCHEMBL28835200 0.71 MCL1 (0.32) MCL1FAAH
SCHEMBL17546682 0.71 FAAH (0.47) MCL1FAAHHPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879956-B1 METHOD FOR PRODUCING CROSSLINKABLE ORGANOPOLYSILOXANE DISPERSIONS WACKER CHEMIE AG (DE) 2013-03-06 EP disclosed
US-8304023-B2 coating with a condensation-curable organopolysiloxanes with silanes to form elastomeric films insoluble in toluene; formed layer has a permanent soft hand and good bulk, no yellowing, free of volatile organic compounds; storage stability, solvent-free WACKER CHEMIE AG (DE) 2012-11-06 US disclosed
EP-2029661-B1 PROCESS FOR THE PRODUCTION OF HIGH-MOLECULAR-WEIGHT ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2011-08-03 EP disclosed
US-7868116-B2 Process for the production of high-molecular-weight organopolysiloxanes WACKER CHEMIE AG (DE) 2011-01-11 US disclosed
US-7582700-B2 Method for the production of emulsions of highly-viscous organopolysiloxanes WACKER CHEMIE AG (DE) 2009-09-01 US disclosed
US-20090198034-A1 PROCESS FOR THE PRODUCTION OF HIGH-MOLECULAR-WEIGHT ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2009-08-06 US disclosed
EP-1721926-B1 Process for the production of dispersions of cross linked organopolysiloxanes WACKER CHEMIE AG (DE) 2009-07-01 EP disclosed
EP-1921203-B1 Treatment of fiberfill fibers with aqueous dispersions of organopolysiloxanes WACKER CHEMIE AG (DE) 2009-06-17 EP disclosed
EP-1921106-A1 Preparation of aqueous dispersions of organopolysiloxanes Wacker Chemie AG (DE) 2008-05-14 EP disclosed
EP-1921203-A1 Treatment of fiberfill fibers with aqueous dispersions of organopolysiloxanes Wacker Chemie AG (DE) 2008-05-14 EP disclosed
EP-1879956-A1 METHOD FOR PRODUCING CROSSLINKABLE ORGANOPOLYSILOXANE DISPERSIONS Wacker Chemie AG (DE) 2008-01-23 EP disclosed
EP-1773920-A1 METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES Wacker Chemie AG (DE) 2007-04-18 EP disclosed
WO-2006119916-A1 METHOD FOR PRODUCING CROSSLINKABLE ORGANOPOLYSILOXANE DISPERSIONS WACKER CHEMIE AG (DE) 2006-11-16 WO disclosed
US-20060258820-A1 Process for preparing dispersions of crosslinked organopolysiloxanes WACKER CHEMIE AG (DE) 2006-11-16 US disclosed
EP-1721926-A1 Process for the production of dispersions of cross linked organopolysiloxanes Wacker Chemie AG (DE) 2006-11-15 EP disclosed
US-7126020-B2 Reactions rapidly complete or proceeds at low temperature such as room temperature; highly viscous and stable products with Si C-bonded radicals containing basic nitrogen WACKER CHEMIE AG (DE) 2006-10-24 US disclosed
EP-1541615-B1 Method for the production of highly viscous organopolysiloxanes WACKER CHEMIE AG (DE) 2006-03-22 EP disclosed
WO-2006015740-A1 METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2006-02-16 WO disclosed
US-20050131243-A1 Process for preparing highly viscous organopolysiloxanes WACKER-CHEMIE GMBH (DE) 2005-06-16 US disclosed
EP-1541615-A1 Method for the production of highly viscous organopolysiloxanes Wacker-Chemie GmbH (DE) 2005-06-15 EP disclosed