Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157138 | 0.83 | EGFR (0.44) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL1776571 | 0.82 | TSHR (0.52) | KMT2AMEN1ALDH1A1KDM4EMITF | |
| SCHEMBL9160411 | 0.80 | CHEK1 (0.49) | GPR17KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL8366302 | 0.80 | ALDH1A1 (0.59) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL31376496 | 0.80 | ALDH1A1 (0.59) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL4484622 | 0.78 | ALDH1A1 (0.56) | GPR17KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL29544940 | 0.78 | ALDH1A1 (0.56) | GPR17KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9156800 | 0.78 | METAP2 (0.42) | GPR17KMT2AMEN1MAPTKDM4E | |
| SCHEMBL29831055 | 0.77 | KDM4E (0.59) | ALDH1A1KDM4EHPGDGLAMETAP2 | |
| SCHEMBL14796728 | 0.77 | KDM4E (0.59) | ALDH1A1KDM4EHPGDGLAMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457099-A | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0577325-A1 | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1994-01-05 | — | — | EP | disclosed |