SCHEMBL4484622

SCHEMBL4484622

O=C(O)Cc1c[nH]c2cc(Br)ccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
TSHR P16473 2/20 0.56
HPGD P15428 2/20 0.56
LMNA P02545 1/20 0.56
GLA P06280 1/20 0.56
CYP2C9 P11712 1/20 0.56
NFKB1 P19838 1/20 0.56
PMP22 Q01453 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
CHRNB2 P17787 1/20 0.54
CHRNA7 P36544 1/20 0.54
CHRNA4 P43681 1/20 0.54
KDM4E B2RXH2 3/20 0.51
MEN1 O00255 2/20 0.49
MAPT P10636 2/20 0.49
KMT2A Q03164 2/20 0.49
POLB P06746 1/20 0.49
GAA P10253 1/20 0.49
THRB P10828 1/20 0.49
DNMT1 P26358 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29544940 1.00 ALDH1A1 (0.56) ALDH1A1TSHRHPGDLMNAGLA
SCHEMBL1519655 0.87 TSHR (0.69) ALDH1A1TSHRHPGDLMNAGLA
SCHEMBL6030041 0.86 CHRNB2 (0.52) NPSR1CHRNB2CHRNA7CHRNA4GAA
SCHEMBL32684054 0.86 CHRNB2 (0.52) NPSR1CHRNB2CHRNA7CHRNA4GAA
SCHEMBL30517178 0.84 CHRNB2 (0.58) ALDH1A1HPGDCHRNB2CHRNA7CHRNA4
SCHEMBL5190454 0.84 CHRNB2 (0.55) LMNACHRNB2CHRNA7CHRNA4MAPT
SCHEMBL6663269 0.82 ALDH1A1 (0.77) ALDH1A1TSHRHPGDLMNAGLA
SCHEMBL29506986 0.82 CHRNB2 (0.56) ALDH1A1LMNACHRNB2CHRNA7CHRNA4
SCHEMBL498040 0.82 CHRNB2 (0.56) ALDH1A1LMNACHRNB2CHRNA7CHRNA4
SCHEMBL4098433 0.81 TSHR (0.77) ALDH1A1TSHRHPGDLMNAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119332255-A Electrochemical synthesis method of arundone derivatives 云南师范大学 2025-01-21 CN claimed
CN-118086928-A Method for electrochemical synthesis of pyrimidoindole derivative under mild condition 湘潭大学 2024-05-28 CN claimed
WO-2007127923-A2 PLANT GROWTH HORMONE REGULATED TRANSCRIPTION FACTORS AND PROMOTERS THEREOF DONALD DANFORTH PLANT SCIENCE CENTER (US) 2007-11-08 WO claimed
US-20050107258-A1 Auxinic analogues of indole-3-acetic acid Life Technologies Corporation 2005-05-19 US claimed
US-6815205-B2 GENERATING PLANT ROOTS INVITROGEN CORPORATION 2004-11-09 US claimed
US-20030087762-A1 Auxinic analogues of indole-3-acetic acid LIFE TECHNOLOGIES, INC. 2003-05-08 US claimed
US-6361999-B1 AMELIORATING DETRIMENTAL EFFECTS OF STRESS ON A PLANT OR PLANT TISSUE, SUCH AS ENVIRONMENTAL STRESS, PHYSICAL STRESS, CHEMICAL STRESS, FROM POLLUTION, CONTAMINATION, DROUGHT, AND LIGHT BY CONTACTING WITH AUXINIC INDOLE ACETIC ACID COMPOUND LIFE TECHNOLOGIES, INC. 2002-03-26 US claimed
EP-0866850-A4 AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID LIFE TECHNOLOGIES INC (US) 2000-11-22 EP claimed
EP-0866850-A1 AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID LIFE TECHNOLOGIES, INC. (US) 1998-09-30 EP claimed
WO-1997020034-A9 AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID 1997-10-16 WO claimed
WO-1997020034-A1 AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID LIFE TECHNOLOGIES, INC. (US) 1997-06-05 WO claimed
CN-119332255-A Electrochemical synthesis method of arundone derivatives 云南师范大学 2025-01-21 CN disclosed
US-12150447-B2 Plant growth regulator UNIVERSITY OF WASHINGTON (US) 2024-11-26 US disclosed
US-12139497-B2 Aryl, heteroaryl, and heterocyclic compounds for treatment of medical disorders ACHILLION PHARMACEUTICALS, INC. (US) 2024-11-12 US disclosed
CN-118086928-A Method for electrochemical synthesis of pyrimidoindole derivative under mild condition 湘潭大学 2024-05-28 CN disclosed
WO-2002002110-A1 USE OF INDOLE-3-ACETIC ACID DERIVATIVES IN MEDICINE CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2002-01-10 WO disclosed
EP-0866850-A4 AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID LIFE TECHNOLOGIES INC (US) 2000-11-22 EP disclosed
EP-0866850-A1 AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID LIFE TECHNOLOGIES, INC. (US) 1998-09-30 EP disclosed
WO-1997020034-A9 AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID 1997-10-16 WO disclosed
WO-1997020034-A1 AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID LIFE TECHNOLOGIES, INC. (US) 1997-06-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087762-A1 Auxinic analogues of indole-3-acetic acid AADAC, AADAT, AANAT ALDH1A1 938/4885TSHR 754/4885HPGD 1986/4885
US-20050107258-A1 Auxinic analogues of indole-3-acetic acid AADAC, AADAT, AANAT ALDH1A1 1052/4885TSHR 795/4885HPGD 2317/4885
US-12139497-B2 Aryl, heteroaryl, and heterocyclic compounds for treatment of medical disorders CFD, F12, F3 ALDH1A1 1682/4885TSHR 744/4885HPGD 380/4885
US-12150447-B2 Plant growth regulator ING2, GHRHR, MYB ALDH1A1 3460/4885TSHR 57/4885HPGD 3249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.