Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154470 | 0.86 | OPRD1 (0.45) | OPRD1HSD17B10SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9157008 | 0.85 | RAB9A (0.53) | OPRD1HSD17B10SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL9156240 | 0.85 | OPRD1 (0.45) | OPRD1HSD17B10SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL770503 | 0.83 | HSD17B10 (0.56) | HSD17B10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL9152133 | 0.82 | NPC1 (0.47) | OPRD1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL9471693 | 0.80 | ALDH1A1 (0.53) | OPRD1HSD17B10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9156655 | 0.79 | ALDH1A1 (0.55) | OPRD1HSD17B10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9157868 | 0.78 | KMT2A (0.57) | OPRD1HSD17B10SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9157855 | 0.78 | KMT2A (0.57) | OPRD1HSD17B10SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9154426 | 0.78 | HSD17B10 (0.71) | OPRD1HSD17B10SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |