Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | PREP | P48147 | 3/20 | 0.41 |
| ▸ | FAP | Q12884 | 3/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157264 | 0.83 | HPGD (0.46) | RAB9ASMN1; SMN2OPRD1MEN1KMT2A | |
| SCHEMBL9158254 | 0.83 | RIPK1 (0.48) | HSD11B1DPP4PREPFAPUTS2R | |
| SCHEMBL9155753 | 0.82 | OPRD1 (0.45) | NPC1RAB9ASMN1; SMN2DRD2DRD4 | |
| SCHEMBL9156791 | 0.82 | RIPK1 (0.44) | HSD11B1DPP4UTS2RDPP8DPP7 | |
| SCHEMBL9471748 | 0.77 | SMN1; SMN2 (0.46) | NPC1RAB9ASMN1; SMN2OPRD1MEN1 | |
| SCHEMBL9152726 | 0.76 | SMN1; SMN2 (0.44) | NPC1RAB9ASMN1; SMN2POLBKMT2A | |
| SCHEMBL9160946 | 0.75 | CREBBP (0.45) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9160859 | 0.75 | HPGD (0.55) | NPC1RAB9ASMN1; SMN2MEN1POLB | |
| SCHEMBL9160936 | 0.75 | CREBBP (0.45) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL770160 | 0.74 | DPP4 (0.54) | NPC1RAB9ASMN1; SMN2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |