Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.30 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155751 | 1.00 | KDM4E (0.34) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9149297 | 0.83 | AHCY (0.45) | RXFP1HSP90AA1 | |
| SCHEMBL9149291 | 0.83 | AHCY (0.45) | RXFP1HSP90AA1 | |
| SCHEMBL10438033 | 0.78 | LMNA (0.31) | ALDH1A1RXFP1 | |
| SCHEMBL10438035 | 0.78 | LMNA (0.31) | ALDH1A1RXFP1 | |
| SCHEMBL9153368 | 0.77 | ADA (0.51) | ALDH1A1HSD17B10 | |
| SCHEMBL9153371 | 0.77 | ADA (0.51) | ALDH1A1HSD17B10 | |
| SCHEMBL12060727 | 0.77 | ADA (0.51) | ALDH1A1HSD17B10 | |
| SCHEMBL9153638 | 0.77 | KDM4E (0.33) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9152465 | 0.76 | ADORA3 (0.51) | ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449664-A | Nucleosides | SYNTEX (U.S.A.) INC. (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0457326-A1 | Antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1991-11-21 | — | — | EP | disclosed |