Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10085254 | 0.94 | LMNA (0.57) | LMNAMAPTSMN1; SMN2MAPK1ALOX12 | |
| SCHEMBL10084519 | 0.93 | LMNA (0.59) | LMNAMAPTSMN1; SMN2MAPK1ALOX12 | |
| SCHEMBL91508 | 0.83 | NPC1 (0.44) | LMNAMAPTSMN1; SMN2MAPK1ALOX12 | |
| SCHEMBL91379 | 0.81 | RAB9A (0.56) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL31461187 | 0.81 | EPHX2 (0.64) | LMNAMAPTSMN1; SMN2MAPK1ALOX12 | |
| SCHEMBL10082036 | 0.78 | RAB9A (0.65) | LMNAMAPTSMN1; SMN2HTTKMT2A | |
| SCHEMBL10084856 | 0.78 | KMT2A (0.49) | LMNAMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL91458 | 0.78 | ALDH1A1 (0.54) | LMNAMAPTSMN1; SMN2MAPK1KMT2A | |
| SCHEMBL10084276 | 0.77 | RAB9A (0.68) | LMNAMAPTSMN1; SMN2HTTKMT2A | |
| SCHEMBL77075 | 0.77 | ATAD2 (0.64) | LMNAMAPTSMN1; SMN2MAPK1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129415-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | LMNA 2321/4885MAPT 2769/4885SMN1; SMN2 4339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.