Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | POLG | P54098 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 5/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 5/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 5/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15532108 | 0.84 | FGFR1 (0.67) | SLC22A6FGFR1ABCB11POLA1POLG | |
| SCHEMBL9417160 | 0.81 | SLC22A6 (0.50) | SLC22A6FGFR1ENPP1NT5EABCB11 | |
| SCHEMBL2107417 | 0.81 | FGFR1 (0.68) | SLC22A6FGFR1ENPP1NT5EABCB11 | |
| SCHEMBL29391225 | 0.81 | FGFR1 (0.68) | SLC22A6FGFR1ENPP1NT5EABCB11 | |
| SCHEMBL19929313 | 0.78 | FGFR1 (0.62) | SLC22A6FGFR1ABCB11POLA1POLG | |
| SCHEMBL9858339 | 0.75 | FGFR1 (0.50) | SLC22A6FGFR1ENPP1NT5EABCB11 | |
| SCHEMBL9417289 | 0.74 | ADORA2A (0.43) | SLC22A6FGFR1ENPP1NT5EPI4KA | |
| SCHEMBL9857536 | 0.74 | FGFR1 (0.65) | SLC22A6FGFR1ENPP1ABCB11POLA1 | |
| SCHEMBL9712232 | 0.74 | FAP (0.64) | SLC22A6FGFR1ENPP1NT5EABCB11 | |
| SCHEMBL2932822 | 0.74 | ADORA2A (0.46) | SLC22A6FGFR1ENPP1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0631583-A1 | ANTIVIRAL PHOSPHONIC ACID DERIVATIVES OF PURINE ANALOGUES | SMITHKLINE BEECHAM PLC (GB) | 1995-01-04 | — | — | EP | disclosed |
| WO-1993019075-A1 | ANTIVIRAL PHOSPHONIC ACID DERIVATIVES OF PURINE ANALOGUES | SMITHKLINE BEECHAM PLC (GB) | 1993-09-30 | — | — | WO | disclosed |