Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.48 |
| ▸ | GABRE | P78334 | 1/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.48 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8786260 | 0.89 | MAOB (0.54) | ALOX5MAOBALDH1A1CSF1RKDM4E | |
| SCHEMBL8784229 | 0.87 | MAOB (0.49) | ALOX5MAOBALDH1A1CSF1RKDM4E | |
| SCHEMBL8785663 | 0.87 | ALOX5 (0.57) | ALOX5MAOBALDH1A1CSF1RKDM4E | |
| SCHEMBL8785092 | 0.85 | CSF1R (0.63) | ALOX5MAOBALDH1A1CSF1RKDM4E | |
| SCHEMBL9306580 | 0.83 | GABRP (0.55) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9153220 | 0.81 | ALOX5 (0.58) | ALOX5MAOBALDH1A1KDM4EGLA | |
| SCHEMBL10672249 | 0.79 | CSF1R (0.74) | ALOX5ALDH1A1CSF1RSMN1; SMN2HPGD | |
| SCHEMBL3316451 | 0.78 | LMNA (0.66) | ALOX5ALDH1A1CSF1RKDM4EGAA | |
| SCHEMBL9149221 | 0.78 | ALOX5 (0.53) | ALOX5ALDH1A1KDM4EGLAGAA | |
| SCHEMBL9153826 | 0.76 | CA1 (0.55) | ALOX5MAOBALDH1A1CSF1RKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514546-B1 | CHROMENE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5278186-A | Substituted with secondary amide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-01-11 | — | — | US | disclosed |
| EP-0514546-A1 | CHROMENE DERIVATIVES, THEIR PRODUCTION AND USE. | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1992-11-25 | — | — | EP | disclosed |
| WO-1991012249-A1 | CHROMENE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-22 | — | — | WO | disclosed |