Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152233 | 0.86 | KDM4E (0.42) | GPR17GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL19353903 | 0.80 | PGK1 (0.45) | GPR17GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL19354163 | 0.79 | GRIN2D (0.42) | GPR17GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9157807 | 0.78 | KDM4E (0.46) | GPR17GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9155186 | 0.76 | ALDH1A1 (0.45) | KDM4EPOLBMAPTHSD17B10ALDH1A1 | |
| SCHEMBL6579033 | 0.76 | GRIN2D (0.54) | GPR17GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3267595 | 0.75 | HTR2C (0.44) | GPR17GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9152213 | 0.73 | ALDH1A1 (0.48) | KDM4EPOLBMAPTHSD17B10ALDH1A1 | |
| SCHEMBL8872158 | 0.69 | GRIN2D (0.46) | GPR17GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28961387 | 0.68 | GRIN2D (0.48) | GPR17GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457099-A | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0577325-A1 | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1994-01-05 | — | — | EP | disclosed |