Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156789 | 0.83 | KDM4E (0.49) | KDM4EKMT2AALDH1A1GLAGAA | |
| SCHEMBL9157617 | 0.79 | DAO (0.40) | KDM4ECYP3A4NOS1CYP2C19NOS2 | |
| SCHEMBL9158309 | 0.76 | DAO (0.38) | KDM4ECYP3A4NOS1CYP2C19NOS2 | |
| SCHEMBL9766046 | 0.76 | L3MBTL1 (0.56) | KDM4ECYP2C19KMT2AALDH1A1GAA | |
| SCHEMBL2239380 | 0.75 | NLRP3 (0.44) | KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9156288 | 0.73 | CNR1 (0.49) | KDM4EKMT2AALDH1A1GLAGAA | |
| SCHEMBL13712986 | 0.72 | LPAR1 (0.52) | KDM4ECYP2C19KMT2ASMN1; SMN2LMNA | |
| SCHEMBL26858390 | 0.70 | KDM4E (0.47) | KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9156787 | 0.69 | ALDH1A1 (0.50) | KDM4EKMT2AALDH1A1GLAGAA | |
| SCHEMBL9159365 | 0.69 | KDM4E (0.49) | KDM4EKMT2AALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457099-A | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0577325-A1 | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1994-01-05 | — | — | EP | disclosed |