Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157255 | 0.83 | KDM4E (0.40) | KDM4ENQO2EGFRKMT2AGAA | |
| SCHEMBL9766046 | 0.79 | L3MBTL1 (0.56) | KDM4EEGFRKMT2AGAAMEN1 | |
| SCHEMBL9161833 | 0.77 | KDM4E (0.57) | KDM4ENQO2EGFRKMT2AGAA | |
| SCHEMBL9156590 | 0.74 | KDM4E (0.54) | KDM4ENQO2EGFRKMT2AGAA | |
| SCHEMBL9156787 | 0.74 | ALDH1A1 (0.50) | KDM4EKMT2AGAAMEN1MAPT | |
| SCHEMBL9159365 | 0.74 | KDM4E (0.49) | KDM4EKMT2AGAAMEN1MAPT | |
| SCHEMBL13191672 | 0.74 | CYP19A1 (0.37) | KDM4ENQO2GAAMAPTALDH1A1 | |
| SCHEMBL728665 | 0.73 | KDM4E (0.49) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL19667052 | 0.72 | NQO2 (0.67) | KDM4ENQO2EGFRKMT2AGAA | |
| SCHEMBL68310 | 0.70 | KDM4E (0.56) | KDM4EEGFRMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457099-A | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0577325-A1 | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1994-01-05 | — | — | EP | disclosed |