Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19043286 | 0.82 | MBOAT4 (0.34) | PTPN1TSHRLMNAADH1BADH1C | |
| SCHEMBL28055769 | 0.78 | ALDH1A1 (0.41) | TSHRLMNAADH1BADH1CADH1A | |
| SCHEMBL6211503 | 0.72 | L3MBTL1 (0.50) | TSHR | |
| SCHEMBL7784378 | 0.72 | L3MBTL1 (0.50) | TSHR | |
| SCHEMBL27274855 | 0.72 | L3MBTL1 (0.50) | TSHR | |
| SCHEMBL5561948 | 0.72 | L3MBTL1 (0.50) | TSHR | |
| SCHEMBL9875114 | 0.72 | L3MBTL1 (0.50) | TSHR | |
| SCHEMBL711369 | 0.72 | L3MBTL1 (0.50) | TSHR | |
| SCHEMBL18585071 | 0.72 | L3MBTL1 (0.50) | TSHR | |
| SCHEMBL1009942 | 0.72 | L3MBTL1 (0.50) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432273-A | Cyclizing a 5-(protected)oxy-5-(heterocyclic base)-3(S)-fluoro-1,2-(S)-pentanediol | EMORY UNIVERSITY (US) | 1995-07-11 | — | — | US | disclosed |