Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155362 | 0.77 | TSHR (0.57) | HSD17B10 | |
| SCHEMBL7904900 | 0.77 | TAAR1 (0.62) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL9153598 | 0.76 | RARB (0.59) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL1815390 | 0.76 | ESR1 (0.59) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL31335119 | 0.75 | HMOX1 (0.40) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL31335193 | 0.75 | HMOX1 (0.40) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL15583726 | 0.75 | TAAR1 (0.59) | HMOX1TAAR1HTR2AHSP90AA1SIGMAR1 | |
| SCHEMBL134452 | 0.75 | TAAR1 (0.59) | HMOX1TAAR1HTR2AHSP90AA1SIGMAR1 | |
| SCHEMBL14838178 | 0.75 | CHRM2 (0.47) | L3MBTL1HTR2ASIGMAR1ADRA2ASLC6A2 | |
| SCHEMBL5490192 | 0.75 | TAAR1 (0.45) | NPC1NFKB1MAPK1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424959-B1 | Organosilylalkyl-aromatic compounds | CONSORTIUM ELEKTROCHEM IND (DE) | 1995-02-01 | — | — | EP | disclosed |
| US-5210247-A | ORGANOSILYLALKYLAROMATIC COMPOUNDS | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1993-05-11 | — | — | US | disclosed |