Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766695 | 0.90 | MAPT (0.52) | MAPTRAB9AL3MBTL1THRBLMNA | |
| SCHEMBL9157318 | 0.87 | LMNA (0.50) | MAPTRAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9156451 | 0.87 | RAB9A (0.48) | MAPTRAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9160679 | 0.84 | MAPT (0.49) | MAPTRAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9156125 | 0.82 | SMN1; SMN2 (0.46) | MAPTRAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9158077 | 0.82 | TAAR1 (0.43) | RAB9AL3MBTL1LMNASMN1; SMN2TP53 | |
| SCHEMBL24687082 | 0.81 | NQO1 (0.54) | NQO1TDP1TSHR | |
| SCHEMBL28616323 | 0.81 | NQO1 (0.74) | NQO1LMNASMN1; SMN2GPR84TDP1 | |
| SCHEMBL10463195 | 0.79 | MAPT (0.50) | MAPTRAB9AL3MBTL1NQO1THRB | |
| SCHEMBL9154338 | 0.79 | RAB9A (0.50) | MAPTRAB9AL3MBTL1NQO1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-B1 | PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5205962-A | Stable liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-27 | — | — | US | disclosed |