Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160679 | 0.97 | MAPT (0.49) | RAB9AL3MBTL1MAPTCYP3A4LMNA | |
| SCHEMBL9157318 | 0.94 | LMNA (0.50) | RAB9AL3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9766695 | 0.93 | MAPT (0.52) | RAB9AL3MBTL1MAPTCYP3A4LMNA | |
| SCHEMBL9158132 | 0.87 | MAPT (0.50) | RAB9AL3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9154293 | 0.86 | NFKB1 (0.51) | RAB9AL3MBTL1MAPTCYP3A4LMNA | |
| SCHEMBL9154167 | 0.85 | RAB9A (0.49) | RAB9AL3MBTL1MAPTCYP3A4LMNA | |
| SCHEMBL9875173 | 0.83 | NFKB1 (0.49) | RAB9AL3MBTL1MAPTCYP3A4LMNA | |
| SCHEMBL9154233 | 0.83 | MAPT (0.51) | RAB9AL3MBTL1MAPTCYP3A4LMNA | |
| SCHEMBL9156125 | 0.83 | SMN1; SMN2 (0.46) | RAB9AL3MBTL1MAPTCYP3A4LMNA | |
| SCHEMBL9152788 | 0.82 | RAB9A (0.53) | RAB9AL3MBTL1MAPTCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-B1 | PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5205962-A | Stable liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-27 | — | — | US | disclosed |