Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766630 | 0.99 | MEN1 (0.30) | MEN1GAAMAPK1KMT2A | |
| SCHEMBL9154681 | 0.97 | GAA (0.33) | GAA | |
| SCHEMBL9159896 | 0.94 | SLC6A2 (0.31) | — | |
| SCHEMBL9766719 | 0.89 | APLNR (0.33) | MEN1GAAMAPK1KMT2A | |
| SCHEMBL9250333 | 0.89 | APLNR (0.34) | MEN1GAAMAPK1KMT2A | |
| SCHEMBL9158982 | 0.89 | TRPV3 (0.32) | — | |
| SCHEMBL9244209 | 0.85 | GAA (0.34) | GAA | |
| SCHEMBL9250236 | 0.84 | GAA (0.36) | GAA | |
| SCHEMBL9249912 | 0.84 | APLNR (0.32) | — | |
| SCHEMBL8774099 | 0.83 | GAA (0.31) | MEN1GAAMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-B1 | PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |