Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153352 | 0.82 | SLC7A5 (0.44) | MEN1KMT2AGAAMAPTHSD17B10 | |
| SCHEMBL9156756 | 0.81 | TSHR (0.61) | MEN1KMT2AGAAMAPTHSD17B10 | |
| Fosopamine SCHEMBL30567798 | 0.80 | MAPT (0.57) | MEN1KMT2AMAPTHSD17B10LMNA | |
| Fosopamine SCHEMBL828844 | 0.80 | MAPT (0.57) | MEN1KMT2AMAPTHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL9152256 | 0.79 | LMNA (0.62) | MEN1KMT2AGAAMAPTHSD17B10 | |
| SCHEMBL28976197 | 0.79 | MAPT (0.66) | CA1CA2MEN1KMT2AGAA | |
| Fosopamine SCHEMBL9152610 | 0.79 | MAPT (0.58) | MEN1KMT2AMAPTHSD17B10LMNA | |
| SCHEMBL9152005 | 0.77 | S1PR2 (0.43) | MEN1KMT2AMAPTHSD17B10LMNA | |
| SCHEMBL9150862 | 0.77 | SMN1; SMN2 (0.49) | CA1CA2MEN1KMT2AGAA | |
| SCHEMBL30666300 | 0.77 | CYP19A1 (0.44) | MEN1KMT2AGAALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430336-B1 | Process for the preparation of 4-O-phosphates of dopamine and dopamine derivatives | ZAMBON SPA (IT) | 1995-02-15 | — | — | EP | disclosed |
| US-5138084-A | PROCESS FOR THE PREPARATION OF 4-O-PHOSPHATES OF DOPAMINE AND DOPAMINE DERIVATIVES | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1992-08-11 | — | — | US | disclosed |
| EP-0430336-A2 | Process for the preparation of 4-O-phosphates of dopamine and dopamine derivatives | ZAMBON GROUP S.p.A. (IT) | 1991-06-05 | — | — | EP | disclosed |