Fluazifop

Fluazifop

SCHEMBL9160098

CC(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)C(=O)O.CC(Oc1ccc(Oc2ccc(Cl)cc2Cl)cc1)C(=O)O

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LIPE Q05469 6/20 0.51
L3MBTL1 Q9Y468 1/20 0.49
FFAR1 O14842 3/20 0.48
LMNA P02545 2/20 0.48
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
POLB P06746 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
RAB9A P51151 1/20 0.46
DAGLA Q9Y4D2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluazifop SCHEMBL9789176 0.95 LIPE (0.49) LIPEL3MBTL1FFAR1LMNAKMT2A
SCHEMBL9160106 0.91 LIPE (0.50) LIPEL3MBTL1FFAR1LMNAKMT2A
Fluazifop SCHEMBL67403 0.87 LMNA (0.62) LIPELMNASMN1; SMN2RAB9A
Fluazifop-P SCHEMBL118853 0.87 LMNA (0.62) LIPELMNASMN1; SMN2RAB9A
Fluazifop SCHEMBL1559717 0.87 LMNA (0.62) LIPELMNASMN1; SMN2RAB9A
Fluazifop-P SCHEMBL29370487 0.87 LMNA (0.62) LIPELMNASMN1; SMN2RAB9A
Fluazifop SCHEMBL29370478 0.87 LMNA (0.62) LIPELMNASMN1; SMN2RAB9A
Fluazifop SCHEMBL1010239 0.87 LMNA (0.62) LIPELMNASMN1; SMN2RAB9A
Fluazifop SCHEMBL7576720 0.86 TDP1 (0.60) LIPEL3MBTL1FFAR1LMNAKMT2A
Fluazifop-P SCHEMBL11006621 0.85 LMNA (0.60) LIPELMNASMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0353248-B1 METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS SEPRACOR INC (US) 1995-03-29 EP disclosed
EP-0353248-A4 METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS 1991-07-17 EP disclosed
EP-0353248-A1 METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS. SEPRACOR INC (US) 1990-02-07 EP disclosed
US-4800162-A ENZYME-ACTIVATED MEMBRANE SEPRACOR, INC. (US) 1989-01-24 US disclosed
WO-1988007582-A1 METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS SEPRACOR, INC. (US) 1988-10-06 WO disclosed