SCHEMBL9160106

SCHEMBL9160106

CC(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)C(=O)OC(=O)C(C)Oc1ccc(Oc2ccc(Cl)cc2Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LIPE Q05469 7/20 0.50
KMT2A Q03164 3/20 0.48
LMNA P02545 2/20 0.48
MEN1 O00255 2/20 0.48
POLB P06746 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
FFAR1 O14842 1/20 0.43
RAB9A P51151 1/20 0.43
DAGLA Q9Y4D2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluazifop SCHEMBL9160098 0.91 LIPE (0.51) LIPEKMT2ALMNAMEN1POLB
Fluazifop SCHEMBL9789176 0.90 LIPE (0.49) LIPEKMT2ALMNAMEN1POLB
Fluazifop-P-Butyl SCHEMBL10474601 0.86 LIPE (0.45) LIPEKMT2ALMNAMEN1POLB
SCHEMBL9362381 0.82 RAB9A (0.56) LIPEKMT2ALMNAMEN1POLB
Diclofop-Methyl SCHEMBL10670222 0.81 FFAR1 (0.48) KMT2ALMNAMEN1SMN1; SMN2L3MBTL1
Haloxyfop-P-Methyl SCHEMBL7199533 0.80 LMNA (0.56) LIPEKMT2ALMNAMEN1POLB
SCHEMBL30661947 0.79 LMNA (0.66) LIPELMNARAB9A
SCHEMBL163792 0.79 LMNA (0.66) LIPELMNARAB9A
SCHEMBL11405401 0.79 MAPK1 (0.50) LIPEKMT2ALMNAMEN1POLB
Fluazifop SCHEMBL7576720 0.79 TDP1 (0.60) LIPEKMT2ALMNAMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0353248-B1 METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS SEPRACOR INC (US) 1995-03-29 EP disclosed
EP-0353248-A4 METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS 1991-07-17 EP disclosed
EP-0353248-A1 METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS. SEPRACOR INC (US) 1990-02-07 EP disclosed
WO-1988007582-A1 METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS SEPRACOR, INC. (US) 1988-10-06 WO disclosed