SCHEMBL9160769

SCHEMBL9160769

CSC(=CN(C)C)C(=O)c1cccc(C(F)(F)F)c1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.58
ALDH1A1 P00352 2/20 0.56
NPSR1 Q6W5P4 1/20 0.45
LMNA P02545 1/20 0.45
SRD5A2 P31213 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MAOB P27338 1/20 0.43
POLB P06746 1/20 0.43
PTGS1 P23219 1/20 0.42
OPRM1 P35372 1/20 0.42
OPRL1 P41146 1/20 0.42
P2RX1 P51575 1/20 0.42
TP53 P04637 1/20 0.42
GAA P10253 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11465983 0.82 CES2 (0.63) CES2ALDH1A1NPSR1LMNASRD5A2
SCHEMBL11465984 0.82 CES2 (0.63) CES2ALDH1A1NPSR1LMNASRD5A2
SCHEMBL9468665 0.81 CES2 (0.58) CES2ALDH1A1NPSR1SRD5A2MEN1
SCHEMBL9468664 0.81 CES2 (0.58) CES2ALDH1A1NPSR1SRD5A2MEN1
SCHEMBL9818400 0.78 RAB9A (0.46) CES2ALDH1A1NPSR1LMNAMEN1
SCHEMBL9159450 0.77 CES2 (0.56) CES2ALDH1A1NPSR1LMNASRD5A2
SCHEMBL9159447 0.77 CES2 (0.56) CES2ALDH1A1NPSR1LMNASRD5A2
Perchlorate SCHEMBL11479560 0.76 CES2 (0.55) CES2ALDH1A1NPSR1LMNASRD5A2
Perchlorate SCHEMBL11479557 0.76 CES2 (0.55) CES2ALDH1A1NPSR1LMNASRD5A2
SCHEMBL11400215 0.76 ALDH1A1 (0.59) CES2ALDH1A1NPSR1LMNASRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5403948-A Treatment of 1-alkoxycarbonylthio-1-(trihaloalkylbenzoyl)-2-(n,n-dimethylamino)ethene with methyl iodide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-04-04 US disclosed
US-5349108-A Chemical intermediates for nonphytotoxic herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-09-20 US disclosed
US-5270467-A 5-substituted-2,4-diphenylpyrimidine derivatives SUMITOMO CHEMICAL CO., LTD. (JP) 1993-12-14 US disclosed
US-5190575-A 5-Methoxy- or -ethoxy, herbicides SUMITOMO CHEMICAL CO., LTD. (JP) 1993-03-02 US disclosed
EP-0425247-A2 5-Substituted-2,4-diphenylpyrimidine derivatives, their production and herbicidal use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-05-02 EP disclosed