Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160946 | 1.00 | CREBBP (0.45) | CREBBPALDH1A1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL9156593 | 0.87 | HPGD (0.57) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL9160859 | 0.86 | HPGD (0.55) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL9152726 | 0.85 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2HPGDKMT2ANPC1 | |
| SCHEMBL9471748 | 0.84 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL9157868 | 0.83 | KMT2A (0.57) | CREBBPALDH1A1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL9157855 | 0.83 | KMT2A (0.57) | CREBBPALDH1A1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL9154036 | 0.78 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL9158344 | 0.76 | PLA2G1B (0.43) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL9162155 | 0.75 | CCKBR (0.44) | ALDH1A1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |