Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9162161 | 1.00 | CCKBR (0.44) | CCKBRHTTEPHX2RAB9ADCUN1D1 | |
| SCHEMBL9155772 | 0.91 | HPGD (0.54) | CCKBRHTTEPHX2RAB9ANPC1 | |
| SCHEMBL9158371 | 0.89 | RAB9A (0.51) | CCKBREPHX2RAB9AMEN1KMT2A | |
| SCHEMBL9471547 | 0.88 | ALDH1A1 (0.50) | CCKBREPHX2RAB9AMEN1KMT2A | |
| SCHEMBL9159792 | 0.85 | EPHX2 (0.50) | CCKBREPHX2DCUN1D1MEN1KMT2A | |
| SCHEMBL9158694 | 0.83 | KMT2A (0.41) | CCKBREPHX2RAB9ADCUN1D1NPC1 | |
| SCHEMBL9155538 | 0.83 | ALDH1A1 (0.42) | CCKBREPHX2RAB9ADCUN1D1NPC1 | |
| SCHEMBL9156611 | 0.82 | ALDH1A1 (0.45) | EPHX2DCUN1D1ALDH1A1NPSR1 | |
| SCHEMBL9159409 | 0.82 | EPHX2 (0.42) | EPHX2RAB9ADCUN1D1NPC1MEN1 | |
| SCHEMBL9156180 | 0.81 | EPHX2 (0.43) | EPHX2RAB9ADCUN1D1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |