SCHEMBL9161408

SCHEMBL9161408

CCC1=C2C(=O)NC(CC)=C2C(=O)N1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12394153 0.69 — —
SCHEMBL988700 0.63 LMNA (0.33) LMNA
SCHEMBL12394128 0.58 PTGS2 (0.30) —
SCHEMBL996564 0.56 PTGS2 (0.33) —
SCHEMBL13207494 0.56 — —
Bicarbonate SCHEMBL3183819 0.56 FFAR3 (0.32) —
SCHEMBL14154751 0.52 — —
SCHEMBL17581127 0.52 — —
SCHEMBL31509083 0.50 LMNA (0.78) LMNA
SCHEMBL10618947 0.50 CRBN (0.37) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9018397-B2 Pyrrolopyrrole derivatives, their manufacture and use BASF SE (DE) 2015-04-28 — — US disclosed
US-20130172575-A1 Pyrrolopyrrole derivatives, their manufacture and use BASF SE (DE) 2013-07-04 — — US disclosed
US-8404864-B2 Pyrrolopyrrole derivatives, their manufacture and use BASF SE (DE) 2013-03-26 — — US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 — — US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 — — US disclosed
US-20110004004-A1 PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE BASF SE (DE) 2011-01-06 — — US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 — — US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 — — US disclosed
EP-0318916-B1 Electrophotographic sensitive material MITA INDUSTRIAL CO LTD (JP) 1995-02-15 — — EP disclosed
US-4925759-A Electrophotographic sensitive material with pyrrolopyrrole and benzidine derivatives MITA INDUSTRIAL CO., LTD. (JP) 1990-05-15 — — US disclosed
EP-0318916-A2 Electrophotographic sensitive material MITA INDUSTRIAL CO. LTD. (JP) 1989-06-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110004004-A1 PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE PPOX, PIN1, DDT LMNA 3319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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