Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | EGFR | P00533 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156590 | 0.85 | KDM4E (0.54) | KDM4EEGFRTSHRPOLBLMNA | |
| SCHEMBL9157617 | 0.81 | DAO (0.40) | KDM4ETSHRLMNAHPGDNQO2 | |
| SCHEMBL9156789 | 0.77 | KDM4E (0.49) | KDM4EEGFRTSHRPOLBLMNA | |
| SCHEMBL19667052 | 0.77 | NQO2 (0.67) | KDM4EEGFRTSHRPOLBHPGD | |
| SCHEMBL9766051 | 0.74 | ALDH1A1 (0.62) | KDM4ETSHRHPGDKMT2AGAA | |
| SCHEMBL4803628 | 0.74 | HTR2A (0.71) | MAPTHTR2ASMN1; SMN2NPSR1 | |
| SCHEMBL9431360 | 0.72 | KDM4E (0.61) | KDM4EEGFRTSHRPOLBLMNA | |
| SCHEMBL9155186 | 0.71 | ALDH1A1 (0.45) | KDM4EPOLBLMNAHPGDMAPT | |
| SCHEMBL9152213 | 0.71 | ALDH1A1 (0.48) | KDM4ETSHRPOLBLMNAHPGD | |
| Hydrochloric Acid SCHEMBL9432073 | 0.69 | KDM4E (0.52) | KDM4EEGFRTSHRPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457099-A | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0577325-A1 | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1994-01-05 | — | — | EP | disclosed |