Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | EGFR | P00533 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9161833 | 0.85 | KDM4E (0.57) | KDM4EEGFRTSHRNQO2AHR | |
| SCHEMBL9158309 | 0.81 | DAO (0.38) | KDM4EEGFRTSHRNQO2HPGD | |
| SCHEMBL19667052 | 0.77 | NQO2 (0.67) | KDM4EEGFRTSHRNQO2AHR | |
| SCHEMBL9156789 | 0.74 | KDM4E (0.49) | KDM4EEGFRTSHRNQO2POLB | |
| SCHEMBL9154966 | 0.74 | ALDH1A1 (0.56) | KDM4ETSHRHPGDGAAALDH1A1 | |
| SCHEMBL9431360 | 0.72 | KDM4E (0.61) | KDM4EEGFRTSHRNQO2AHR | |
| SCHEMBL9153152 | 0.71 | LMNA (0.42) | KDM4EHTR2APOLBLMNAHPGD | |
| SCHEMBL9157725 | 0.71 | ALDH1A1 (0.46) | KDM4ETSHRHTR2APOLBLMNA | |
| SCHEMBL4119112 | 0.69 | KDM4E (0.55) | KDM4EHTR2AMAPTCYP2C19 | |
| SCHEMBL3949025 | 0.69 | NOS2 (0.51) | CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457099-A | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0577325-A1 | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1994-01-05 | — | — | EP | disclosed |