Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 14/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9171172 | 0.93 | FAAH (0.56) | FAAHCNR2CNR1TP53MAPT | |
| SCHEMBL9167683 | 0.90 | FAAH (0.59) | FAAHCNR2CNR1TP53MAPT | |
| SCHEMBL9166613 | 0.86 | CNR2 (0.53) | FAAHCNR2CNR1MGLL | |
| SCHEMBL9171210 | 0.83 | FAAH (0.46) | FAAHCNR2CNR1 | |
| SCHEMBL9168034 | 0.82 | FAAH (0.49) | FAAHCNR2CNR1NPC1ALDH1A1 | |
| SCHEMBL9565608 | 0.81 | FAAH (0.67) | FAAHTP53 | |
| SCHEMBL9164926 | 0.80 | FAAH (0.51) | FAAHCNR2CNR1NPC1RAB9A | |
| SCHEMBL9164968 | 0.79 | PLA2G2A (0.58) | FAAHCNR2CNR1ALDH1A1TSHR | |
| SCHEMBL907591 | 0.78 | MGLL (0.65) | TP53MAPTNPC1ALDH1A1TSHR | |
| SCHEMBL1163051 | 0.76 | GAA (0.66) | TP53MAPTNPC1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446189-A | Diester intermediates for diacid enzyme inhibitor | HOFFMANN-LA ROCHE INC. (US) | 1995-08-29 | — | — | US | disclosed |
| US-5324747-A | Treatment of inflammatory diseases | HOFFMANN-LA ROCHE INC. (US) | 1994-06-28 | — | — | US | disclosed |
| EP-0579066-A2 | N-substituted anilines | F. HOFFMANN-LA ROCHE AG (CH) | 1994-01-19 | — | — | EP | disclosed |