SCHEMBL9162965

SCHEMBL9162965

Cc1cc(C)cc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4ccc(C)cc4C)cc3)cc2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
CYP2C19 P33261 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
APP P05067 2/20 0.38
SMN1; SMN2 Q16637 3/20 0.34
LMNA P02545 3/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32
PSMB5 P28074 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12388884 0.92 SMN1; SMN2 (0.38) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E
SCHEMBL13929906 0.92 ALDH1A1 (0.37) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E
SCHEMBL2846530 0.92 SMN1; SMN2 (0.38) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E
SCHEMBL13929895 0.92 SMN1; SMN2 (0.38) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E
SCHEMBL23937009 0.91 HSD17B1 (0.38) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E
SCHEMBL19270237 0.91 ALDH1A1 (0.38) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E
SCHEMBL12388883 0.89 SMN1; SMN2 (0.38) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E
SCHEMBL14256382 0.89 LMNA (0.35) ALDH1A1CYP2C19KDM4ESMN1; SMN2LMNA
SCHEMBL12388890 0.89 SMN1; SMN2 (0.39) ALDH1A1MAPTL3MBTL1KDM4ETDP1
SCHEMBL15946725 0.89 SMN1; SMN2 (0.41) ALDH1A1MAPTCYP2C19L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0390196-B1 Electrophotosensitive material MITA INDUSTRIAL CO LTD (JP) 1995-09-20 EP disclosed
EP-0385440-B1 Electrophotosensitive material MITA INDUSTRIAL CO LTD (JP) 1995-05-03 EP disclosed
EP-0314195-B1 Electrophotographic sensitive material MITA INDUSTRIAL CO LTD (JP) 1995-03-22 EP disclosed
US-5153088-A High sensitivity mixture also with charge transferring substituted phenyl diamines MITA INDUSTRIAL CO., LTD. (JP) 1992-10-06 US disclosed
US-5059503-A Used for copying machine MITA INDUSTRIAL CO., LTD. (JP) 1991-10-22 US disclosed
EP-0390196-A2 Electrophotosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1990-10-03 EP disclosed
US-4877702-A PERYLENE TYPE ELECTRIC CHARGE GENERATING SUBSTANCE AND DIAMINE DERIVATIVE AS ELECTRIC CHARGE TRANSFERRING SUBSTANCE MITA INDUSTRIAL CO., LTD. (JP) 1989-10-31 US disclosed
EP-0314195-A2 Electrophotographic sensitive material MITA INDUSTRIAL CO. LTD. (JP) 1989-05-03 EP disclosed