Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | DBH | P09172 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339603 | 0.77 | TYR (0.54) | TYRMMP2DBHALDH1A1CYP3A4 | |
| SCHEMBL14425214 | 0.72 | TYR (0.50) | TYRMMP2DBHTDP1MAPT | |
| SCHEMBL9865577 | 0.72 | TYR (0.56) | TYRMMP2DBHALDH1A1ALOX15 | |
| SCHEMBL21465807 | 0.72 | TYR (0.50) | TYRMMP2DBHALOX15CASP1 | |
| SCHEMBL11193755 | 0.72 | TYR (0.56) | TYRMMP2DBHALDH1A1CYP3A4 | |
| SCHEMBL23250747 | 0.72 | TYR (0.50) | TYRMMP2DBHCA6CA14 | |
| SCHEMBL1109012 | 0.72 | TYR (0.45) | TYRMMP2DBHALDH1A1THRB | |
| Gamma-Thujaplicin SCHEMBL10668692 | 0.72 | TYR (1.00) | TYRMMP2DBHALDH1A1CYP3A4 | |
| SCHEMBL11441247 | 0.71 | MEN1 (0.50) | ALDH1A1CYP3A4ALOX15HSD17B10THRB | |
| SCHEMBL916360 | 0.69 | MAPK1 (0.59) | TYRMMP2DBHALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018105-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | KINESID THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | US | disclosed |
| US-20240018105-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | KINESID THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | US | disclosed |
| WO-2021076945-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |
| WO-2020138265-A1 | METHOD, APPARATUS AND PROGRAM FOR ASSESSING AMYLOID FORMATION | 国立大学法人室蘭工業大学 | 2020-07-02 | — | — | WO | disclosed |
| US-8153440-B2 | Methods for altering surface characteristics of microspheres | LUMINEX CORPORATION (US) | 2012-04-10 | — | — | US | disclosed |
| US-8153440-B2 | Methods for altering surface characteristics of microspheres | LUMINEX CORPORATION (US) | 2012-04-10 | — | — | US | disclosed |
| US-8153440-B2 | Methods for altering surface characteristics of microspheres | LUMINEX CORPORATION (US) | 2012-04-10 | — | — | US | disclosed |
| US-20110086431-A1 | Methods for Altering Surface Characteristics of Microspheres | LUMINEX CORPORATION (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086431-A1 | Methods for Altering Surface Characteristics of Microspheres | LUMINEX CORPORATION (US) | 2011-04-14 | — | — | US | disclosed |
| US-4739083-A | REACTING 1,3-DIOXAN-4-ONE WITH (AMINE OR IMINE) SUBSTITUTED AMIDE | DAICEL CHEMICAL INDUSTRIES LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| US-4638062-A | 3-acylamino-2-oxo-1-azetidinesulfonic acids | E. R. SQUIBB & SONS, INC. (US) | 1987-01-20 | — | — | US | disclosed |
| US-4563453-A | ANTIINFLAMMATORY, ANALGESIC | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-07 | — | — | US | disclosed |
| US-4540692-A | Anti-inflammatory N-(1-oxo-2,4,6-cycloheptatrienyl)2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide derivatives, compositions, and method of use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-09-10 | — | — | US | disclosed |
| EP-0138223-A2 | Thiazine derivatives, processes for preparation thereof and pharmaceutical conmposition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-04-24 | — | — | EP | disclosed |
| US-4382088-A | DIABETIC COMPLICATIONS, ALDOSE REDUCTASE INHIBITORS | AYERST, MCKENNA & HARRISON, INC. (CA) | 1983-05-03 | — | — | US | disclosed |
| US-4183955-A | Troponyl-oxamic acid derivatives for treating allergic conditions | Ayerst. McKenna & Harrison Limited (CA) | 1980-01-15 | — | — | US | disclosed |
| US-4130649-A | Cyclohepta [B]pyridine-2-carboxylic acid derivatives | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-12-19 | — | — | US | disclosed |
| US-4125625-A | ANTIALLERGENS | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-11-14 | — | — | US | disclosed |
| US-4057556-A | ANTIALLERGENS | AYERST, MCKENNA & HARRISON LTD. (CA) | 1977-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018105-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | TXNRD2, TXNRD1, SDHB | TYR 512/4885MMP2 4478/4885DBH 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.