Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | DBH | P09172 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | BLVRB | P30043 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10616379 | 0.75 | MEN1 (1.00) | MAPK1TDP1MEN1KMT2AHSP90AA1 | |
| SCHEMBL234461 | 0.74 | ALDH1A1 (0.58) | MAPK1TDP1MEN1KMT2AHSP90AA1 | |
| SCHEMBL31217749 | 0.73 | ALDH1A1 (0.38) | MAPK1TDP1MEN1KMT2AHSP90AA1 | |
| SCHEMBL10339603 | 0.73 | TYR (0.54) | MAPK1TDP1MEN1KMT2AHSP90AA1 | |
| SCHEMBL107699 | 0.73 | — | — | |
| SCHEMBL3316934 | 0.72 | PTGS2 (0.48) | MAPK1TDP1MEN1KMT2AHSP90AA1 | |
| SCHEMBL24265884 | 0.70 | KDM4E (0.42) | MAPK1TDP1MEN1KMT2AHSP90AA1 | |
| SCHEMBL31493923 | 0.70 | ALDH1A1 (0.50) | MAPK1TDP1MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL28416859 | 0.70 | CA2 (0.50) | MAPK1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL3673256 | 0.70 | ALDH1A1 (0.50) | MAPK1TDP1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018105-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | KINESID THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | US | disclosed |
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |
| WO-2021076945-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |
| US-10980754-B2 | Anti-fungal compounds | SAINT LOUIS UNIVERSITY (US) | 2021-04-20 | — | — | US | disclosed |
| US-10980754-B2 | Anti-fungal compounds | SAINT LOUIS UNIVERSITY (US) | 2021-04-20 | — | — | US | disclosed |
| WO-2020138265-A1 | METHOD, APPARATUS AND PROGRAM FOR ASSESSING AMYLOID FORMATION | 国立大学法人室蘭工業大学 | 2020-07-02 | — | — | WO | disclosed |
| US-10463664-B2 | Inhibitors of HSV nucleotidyl transferases and uses therefor | SAINT LOUIS UNIVERSITY (US) | 2019-11-05 | — | — | US | disclosed |
| US-10329542-B2 | HBV RNAse H purification and enzyme inhibitors | SAINT LOUIS UNIVERSITY (US) | 2019-06-25 | — | — | US | disclosed |
| US-10329542-B2 | HBV RNAse H purification and enzyme inhibitors | SAINT LOUIS UNIVERSITY (US) | 2019-06-25 | — | — | US | disclosed |
| US-20190099385-A1 | ANTI-FUNGAL COMPOUNDS | SAINT LOUIS UNIVERSITY (US) | 2019-04-04 | — | — | US | disclosed |
| US-7259187-B2 | Tropolone derivatives | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-08-21 | — | — | US | disclosed |
| US-7259187-B2 | Tropolone derivatives | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-08-21 | — | — | US | disclosed |
| EP-1802973-A2 | METHODS FOR ALTERING SURFACE CHARACTERISTICS OF MICROSPHERES | Luminex Corporation (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006044275-A2 | METHODS FOR ALTERING SURFACE CHARACTERISTICS OF MICROSPHERES | LUMINEX CORPORATION (US) | 2006-04-27 | — | — | WO | disclosed |
| US-20060078997-A1 | Methods for altering surface characteristics of microspheres | LUMINEX CORPORATION | 2006-04-13 | — | — | US | disclosed |
| US-4754041-A | 3-acylamino-2-oxo-1-azetidinesulfonic acids | E. R. SQUIBB & SONS, INC. (US) | 1988-06-28 | — | — | US | disclosed |
| US-4638062-A | 3-acylamino-2-oxo-1-azetidinesulfonic acids | E. R. SQUIBB & SONS, INC. (US) | 1987-01-20 | — | — | US | disclosed |
| US-4183955-A | Troponyl-oxamic acid derivatives for treating allergic conditions | Ayerst. McKenna & Harrison Limited (CA) | 1980-01-15 | — | — | US | disclosed |
| US-4125625-A | ANTIALLERGENS | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-11-14 | — | — | US | disclosed |
| US-4057556-A | ANTIALLERGENS | AYERST, MCKENNA & HARRISON LTD. (CA) | 1977-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018105-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | TXNRD2, TXNRD1, SDHB | MAPK1 2798/4885TDP1 503/4885MEN1 2972/4885 |
| US-20190099385-A1 | ANTI-FUNGAL COMPOUNDS | ERG28, NANS, DPM1 | MAPK1 1371/4885TDP1 3088/4885MEN1 1879/4885 |
| US-10980754-B2 | Anti-fungal compounds | ERG28, NANS, DPM1 | MAPK1 1371/4885TDP1 3088/4885MEN1 1879/4885 |
| US-10463664-B2 | Inhibitors of HSV nucleotidyl transferases and uses therefor | TYMP, TYMS, NAMPT | MAPK1 3786/4885TDP1 218/4885MEN1 2603/4885 |
| US-10329542-B2 | HBV RNAse H purification and enzyme inhibitors | RNASEH1, RNASE1, RNASEL | MAPK1 3951/4885TDP1 1014/4885MEN1 2978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.