Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | DBH | P09172 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CA3 | P07451 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14425214 | 0.77 | TYR (0.50) | TYRMMP2DBHCA1CA2 | |
| SCHEMBL916337 | 0.77 | TYR (0.56) | TYRMMP2DBHCA12CA1 | |
| SCHEMBL11193755 | 0.77 | TYR (0.56) | TYRMMP2DBHCA1CA2 | |
| SCHEMBL9865577 | 0.77 | TYR (0.56) | TYRMMP2DBHCA12CA1 | |
| SCHEMBL21465807 | 0.77 | TYR (0.50) | TYRMMP2DBHCA1CA2 | |
| SCHEMBL23250747 | 0.77 | TYR (0.50) | TYRMMP2DBHCA1CA2 | |
| SCHEMBL728289 | 0.73 | MMP2 (0.64) | TYRMMP2DBHMAPTALOX15 | |
| SCHEMBL916360 | 0.73 | MAPK1 (0.59) | TYRMMP2DBHMAPTKDM4E | |
| SCHEMBL10668284 | 0.73 | TSHR (0.60) | TYRMMP2DBHCA12CA1 | |
| SCHEMBL17063224 | 0.71 | LMNA (0.58) | TYRMMP2DBHCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2237962-A | — | — | None | — | — | JP | disclosed |
| JP-2237964-A | — | — | None | — | — | JP | disclosed |
| CN-109562050-B | Gel-like composition | 株式会社钟化 | 2022-05-10 | — | — | CN | disclosed |
| EP-3533438-A1 | GELATINOUS COMPOSITION | Kaneka Corporation (JP) | 2019-09-04 | — | — | EP | disclosed |
| US-20190247285-A1 | GELATINOUS COMPOSITION | KANEKA CORPORATION (JP) | 2019-08-15 | — | — | US | disclosed |
| US-7259187-B2 | Tropolone derivatives | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-08-21 | — | — | US | disclosed |
| US-7259187-B2 | Tropolone derivatives | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-08-21 | — | — | US | disclosed |
| JP-H02237962-A | TROPOLONE FLUOROBENZOIC ACID ESTER DERIVATIVE | NIPPON SHOKUBAI KAGAKU KOGYO CO LTD | 1990-09-20 | — | — | JP | disclosed |
| JP-H02237964-A | TROPOLONE DERIVATIVE | NIPPON SHOKUBAI KAGAKU KOGYO CO LTD | 1990-09-20 | — | — | JP | disclosed |
| US-4883758-A | Biologically pure culture of the microorganism Streptomycas tropolofaciens used for producing 3,7-dihydroxytropolone and antitumor use | BRISTOL-MYERS COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4833079-A | CULTURE OF STREPTOMYCES | BRISTOL-MYERS COMPANY (US) | 1989-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190247285-A1 | GELATINOUS COMPOSITION | DAGLA, GLA, DAGLB | TYR 4599/4885MMP2 226/4885DBH 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.