Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445841 | 1.00 | LMNA (0.45) | LMNAESR1FABP4FABP5ACP3 | |
| SCHEMBL9445842 | 1.00 | LMNA (0.45) | LMNAESR1FABP4FABP5ACP3 | |
| SCHEMBL11556826 | 0.88 | FABP4 (0.49) | LMNAFABP4FABP5PPARAKEAP1 | |
| SCHEMBL27961315 | 0.83 | ESR1 (0.44) | ESR1ACP3PPARAALDH1A1L3MBTL1 | |
| SCHEMBL23057886 | 0.81 | ALDH1A1 (0.49) | ESR1ACP3PPARAALDH1A1L3MBTL1 | |
| SCHEMBL29974504 | 0.81 | ALDH1A1 (0.49) | ESR1ACP3PPARAALDH1A1L3MBTL1 | |
| SCHEMBL9445847 | 0.81 | KMT2A (0.53) | LMNAFABP4FABP5ALDH1A1L3MBTL1 | |
| SCHEMBL9445850 | 0.81 | KMT2A (0.53) | LMNAFABP4FABP5ALDH1A1L3MBTL1 | |
| SCHEMBL9163395 | 0.81 | KMT2A (0.53) | LMNAFABP4FABP5ALDH1A1L3MBTL1 | |
| SCHEMBL21727863 | 0.80 | ESR1 (0.41) | LMNAESR1ACP3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270342-A | Acetamide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | disclosed |