SCHEMBL916402

SCHEMBL916402

C=Cc1ccc(-c2c(O)c(=O)c2=O)cc1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 1/20 0.34
TRPA1 O75762 1/20 0.32
HDAC2 Q92769 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
HDAC8 Q9BY41 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12432628 0.72 ALOX12 (0.42) ALDH1A1TDP1TSHRMEN1KMT2A
SCHEMBL1109016 0.72 CYP3A4 (0.43) ALDH1A1TDP1TSHRMEN1KMT2A
SCHEMBL2203880 0.72 MAPT (0.59) HDAC2MEN1KMT2ATP53MAPT
SCHEMBL13290009 0.71 SERPINE1 (0.41) ALDH1A1MAPT
SCHEMBL12432447 0.70 MAPT (0.56) HDAC2MEN1KMT2ATP53MAPT
SCHEMBL593791 0.69 ALDH1A1 (0.79) ALDH1A1TDP1TSHRTRPA1HDAC2
SCHEMBL583978 0.69 ALDH1A1 (0.79) ALDH1A1TDP1TSHRTRPA1HDAC2
SCHEMBL1231666 0.69 ALDH1A1 (0.58) ALDH1A1TDP1TSHRHDAC2MEN1
SCHEMBL3671202 0.68 HDAC4 (0.56) ALDH1A1HDAC2MEN1KMT2ATP53
SCHEMBL61415 0.68 ALDH1A1 (0.44) ALDH1A1TSHRMEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153440-B2 Methods for altering surface characteristics of microspheres LUMINEX CORPORATION (US) 2012-04-10 US disclosed
US-8153440-B2 Methods for altering surface characteristics of microspheres LUMINEX CORPORATION (US) 2012-04-10 US disclosed
US-8153440-B2 Methods for altering surface characteristics of microspheres LUMINEX CORPORATION (US) 2012-04-10 US disclosed
US-20110086431-A1 Methods for Altering Surface Characteristics of Microspheres LUMINEX CORPORATION (US) 2011-04-14 US disclosed
US-20110086431-A1 Methods for Altering Surface Characteristics of Microspheres LUMINEX CORPORATION (US) 2011-04-14 US disclosed
US-20110086431-A1 Methods for Altering Surface Characteristics of Microspheres LUMINEX CORPORATION (US) 2011-04-14 US disclosed
US-7867774-B2 Methods for altering surface characteristics of microspheres LUMINEX CORPORATION (US) 2011-01-11 US disclosed
US-7867774-B2 Methods for altering surface characteristics of microspheres LUMINEX CORPORATION (US) 2011-01-11 US disclosed
US-7867774-B2 Methods for altering surface characteristics of microspheres LUMINEX CORPORATION (US) 2011-01-11 US disclosed
EP-1802973-B1 METHODS FOR ALTERING SURFACE CHARACTERISTICS OF MICROSPHERES LUMINEX CORP (US) 2010-05-05 EP disclosed
EP-1802973-A2 METHODS FOR ALTERING SURFACE CHARACTERISTICS OF MICROSPHERES Luminex Corporation (US) 2007-07-04 EP disclosed
WO-2006044275-A2 METHODS FOR ALTERING SURFACE CHARACTERISTICS OF MICROSPHERES LUMINEX CORPORATION (US) 2006-04-27 WO disclosed
US-20060078997-A1 Methods for altering surface characteristics of microspheres LUMINEX CORPORATION 2006-04-13 US disclosed