Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 4/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4584577 | 0.83 | CYP3A4 (0.56) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| SCHEMBL12432628 | 0.77 | ALOX12 (0.42) | TDP1ALDH1A1TP53HSD17B10ALOX15 | |
| SCHEMBL2202541 | 0.77 | SERPINE1 (0.42) | ALDH1A1HSD17B10MAPTKDM4EACHE | |
| SCHEMBL2203880 | 0.76 | MAPT (0.59) | CYP3A4TP53ALOX15MAPTMEN1 | |
| SCHEMBL13290009 | 0.76 | SERPINE1 (0.41) | ALDH1A1HSD17B10MAPTKDM4EACHE | |
| SCHEMBL12432447 | 0.74 | MAPT (0.56) | CYP3A4TP53ALOX15MAPTMEN1 | |
| SCHEMBL3671202 | 0.72 | HDAC4 (0.56) | CYP3A4ALDH1A1TP53HSD17B10CA14 | |
| SCHEMBL61415 | 0.72 | ALDH1A1 (0.44) | ALDH1A1TP53HSD17B10ALOX15HIF1A | |
| SCHEMBL916402 | 0.72 | ALDH1A1 (0.44) | TDP1ALDH1A1TP53MAPTMEN1 | |
| SCHEMBL28352365 | 0.71 | TDP1 (0.48) | CYP3A4TDP1ALDH1A1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153440-B2 | Methods for altering surface characteristics of microspheres | LUMINEX CORPORATION (US) | 2012-04-10 | — | — | US | disclosed |
| US-20110086431-A1 | Methods for Altering Surface Characteristics of Microspheres | LUMINEX CORPORATION (US) | 2011-04-14 | — | — | US | disclosed |
| US-7867774-B2 | Methods for altering surface characteristics of microspheres | LUMINEX CORPORATION (US) | 2011-01-11 | — | — | US | disclosed |