Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026198 | 0.78 | LMNA (0.39) | ALDH1A1LMNAKDM4EGAAHTT | |
| SCHEMBL9026846 | 0.74 | FBP1 (0.31) | — | |
| SCHEMBL9026413 | 0.74 | LMNA (0.40) | ALDH1A1LMNAKDM4EGAAHTT | |
| SCHEMBL9026344 | 0.67 | — | — | |
| SCHEMBL13751489 | 0.59 | XDH (0.44) | ALDH1A1KDM4EGAAKDM4C | |
| SCHEMBL16210289 | 0.59 | KDM4C (0.37) | ALDH1A1LMNAKDM4EGAANPSR1 | |
| SCHEMBL31094879 | 0.58 | GLA (0.43) | ALDH1A1LMNAKDM4EGAAHTT | |
| SCHEMBL13751491 | 0.57 | FBP1 (0.43) | ALDH1A1LMNAKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL2565733 | 0.57 | NPSR1 (0.36) | ALDH1A1LMNAKDM4EGAAHTT | |
| SCHEMBL1224786 | 0.55 | TYMP (0.45) | ALDH1A1KDM4EGAAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459142-A | Autoimmune disease, atherosclerosis, antiischemic agents and nephritis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-10-17 | — | — | US | disclosed |
| EP-0511879-B1 | Pyrazine derivatives | OTSUKA PHARMA CO LTD (JP) | 1995-03-22 | — | — | EP | disclosed |
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |