⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026846 | 0.79 | FBP1 (0.31) | — | |
| SCHEMBL9160957 | 0.76 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL9471009 | 0.71 | CREBBP (0.36) | — | |
| SCHEMBL9025791 | 0.70 | KMT2A (0.36) | — | |
| SCHEMBL9687418 | 0.68 | POLB (0.34) | — | |
| SCHEMBL9687941 | 0.67 | EZH2 (0.40) | — | |
| SCHEMBL9687454 | 0.66 | MEN1 (0.39) | — | |
| SCHEMBL29581437 | 0.55 | — | — | |
| SCHEMBL19402606 | 0.52 | TSHR (0.36) | — | |
| SCHEMBL5587286 | 0.52 | IDO1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5238938-A | Nephrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0411150-A1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |