Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.39 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.39 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.39 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.39 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9168493 | 0.85 | PLA2G2A (0.44) | MEN1KMT2AALDH1A1CETPCYP3A4 | |
| SCHEMBL9170650 | 0.84 | ALOX15 (0.54) | ALOX15MEN1KMT2AKDM4ERECQL | |
| SCHEMBL9170924 | 0.78 | CETP (0.45) | MEN1KMT2AALDH1A1HPGDCETP | |
| Hexadecanoic Acid Benzyl Ester SCHEMBL1356933 | 0.77 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1HPGDPTPN1 | |
| Benzyl Tetradecanoate SCHEMBL351857 | 0.77 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1HPGDPTPN1 | |
| SCHEMBL6832910 | 0.77 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1HPGDPTPN1 | |
| SCHEMBL1322235 | 0.77 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1HPGDPTPN1 | |
| SCHEMBL6832914 | 0.77 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1HPGDPTPN1 | |
| SCHEMBL6834887 | 0.77 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1HPGDPTPN1 | |
| SCHEMBL6834886 | 0.77 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1HPGDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446189-A | Diester intermediates for diacid enzyme inhibitor | HOFFMANN-LA ROCHE INC. (US) | 1995-08-29 | — | — | US | disclosed |
| US-5324747-A | Treatment of inflammatory diseases | HOFFMANN-LA ROCHE INC. (US) | 1994-06-28 | — | — | US | disclosed |
| EP-0579066-A2 | N-substituted anilines | F. HOFFMANN-LA ROCHE AG (CH) | 1994-01-19 | — | — | EP | disclosed |