Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.43 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.43 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.43 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.40 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9164868 | 0.84 | ALOX15 (0.49) | ALOX15TOP2AKDM4EMEN1RECQL | |
| SCHEMBL9173673 | 0.80 | PLA2G2A (0.68) | ALOX15PLA2G2ABLMMEN1KMT2A | |
| SCHEMBL9172169 | 0.80 | PLA2G2A (0.68) | ALOX15PLA2G2ABLMMEN1KMT2A | |
| SCHEMBL9168583 | 0.80 | PLA2G2A (0.64) | PLA2G2ABLMCYSLTR2CYSLTR1 | |
| SCHEMBL15558761 | 0.78 | ALOX15 (0.62) | ALOX15TOP2AKDM4EMEN1RECQL | |
| SCHEMBL15558002 | 0.78 | ALOX15 (0.62) | ALOX15TOP2AKDM4EMEN1RECQL | |
| SCHEMBL15558293 | 0.77 | ALOX15 (0.60) | ALOX15TOP2AKMT2ACYSLTR2CYSLTR1 | |
| SCHEMBL15558294 | 0.77 | ALOX15 (0.60) | ALOX15TOP2AKMT2ACYSLTR2CYSLTR1 | |
| SCHEMBL15557956 | 0.76 | ALOX15 (0.63) | ALOX15TOP2AKDM4EMEN1RECQL | |
| SCHEMBL15558542 | 0.76 | ALOX15 (0.63) | ALOX15TOP2AKDM4EMEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446189-A | Diester intermediates for diacid enzyme inhibitor | HOFFMANN-LA ROCHE INC. (US) | 1995-08-29 | — | — | US | disclosed |
| US-5324747-A | Treatment of inflammatory diseases | HOFFMANN-LA ROCHE INC. (US) | 1994-06-28 | — | — | US | disclosed |
| EP-0579066-A2 | N-substituted anilines | F. HOFFMANN-LA ROCHE AG (CH) | 1994-01-19 | — | — | EP | disclosed |