Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115704 | 0.81 | NCF1 (0.49) | PIK3CDALDH1A1KDM4ETDP1MAPT | |
| SCHEMBL2115701 | 0.81 | NCF1 (0.49) | PIK3CDALDH1A1KDM4ETDP1MAPT | |
| SCHEMBL15865468 | 0.72 | PIK3CD (0.57) | PIK3CDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL22263486 | 0.71 | POLB (0.56) | ALDH1A1KDM4ETDP1L3MBTL1MAPT | |
| SCHEMBL14872902 | 0.71 | ALDH1A1 (0.52) | ALDH1A1KDM4ETDP1MAPTHPGD | |
| SCHEMBL22198990 | 0.69 | EGFR (0.50) | PIK3CDALDH1A1KDM4ETDP1MAPT | |
| SCHEMBL845236 | 0.69 | ALOX15 (0.59) | PIK3CDALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL715736 | 0.69 | ALOX15 (0.59) | PIK3CDALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL715249 | 0.68 | HPGD (0.43) | PIK3CDALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL20061318 | 0.67 | PDE10A (0.57) | ALDH1A1KDM4ETDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058109-A1 | FUSED BICYCLIC PYRROLE AND IMIDAZOLE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2011-05-19 | — | — | WO | disclosed |