Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91665 | 0.98 | RAPGEF4 (0.31) | RAPGEF4 | |
| SCHEMBL91680 | 0.94 | — | — | |
| SCHEMBL91784 | 0.93 | — | — | |
| SCHEMBL25573712 | 0.83 | GABRA1 (0.36) | GABRA1GABRB2 | |
| SCHEMBL24390818 | 0.82 | RAPGEF4 (0.33) | GABRA1GABRB2RAPGEF4 | |
| SCHEMBL14586541 | 0.81 | NAAA (0.35) | GABRA1GABRB2 | |
| SCHEMBL91882 | 0.81 | NAAA (0.35) | GABRA1GABRB2 | |
| SCHEMBL91800 | 0.80 | — | — | |
| SCHEMBL91696 | 0.79 | CYP1A2 (0.33) | — | |
| SCHEMBL91749 | 0.78 | AR (0.35) | RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-7419706-B2 | Liquid crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-09-02 | — | — | US | disclosed |