Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410091 | 0.74 | IDO1 (0.67) | IDO1ALDH1A1HSD17B10RAB9AKDM4E | |
| SCHEMBL11222030 | 0.72 | RAB9A (0.64) | ALDH1A1NPC1RAB9AKDM4EGAA | |
| SCHEMBL15239247 | 0.72 | IDO1 (0.43) | IDO1ALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL2894776 | 0.72 | KMT2A (0.66) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL67321 | 0.70 | ESR2 (0.55) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL1197399 | 0.70 | SMN1; SMN2 (0.61) | ALDH1A1NPC1RAB9AGAAMAPT | |
| SCHEMBL17005531 | 0.70 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9AGAAHPGD | |
| SCHEMBL9544540 | 0.70 | SCN9A (0.44) | NPC1RAB9AKDM4EGAAMAPT | |
| SCHEMBL18609949 | 0.68 | IDO1 (0.59) | IDO1ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL321265 | 0.67 | PGR (0.59) | ALDH1A1NPC1RAB9AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455225-B1 | Method for measuring the percentage of glycation of a particular protein | NACALAI TESQUE INC (JP) | 1995-03-29 | — | — | EP | disclosed |
| EP-0455225-A2 | Method for measuring the percentage of glycation of a particular protein | NACALAI TESQUE, INC. (JP) | 1991-11-06 | — | — | EP | disclosed |