Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9164474 | 0.72 | FFAR1 (0.40) | HTR2CHTR2BTSHRUCHL1CARM1 | |
| SCHEMBL7041221 | 0.70 | ADORA2A (0.42) | KDM4ELMNAMAPTTSHRALDH1A1 | |
| SCHEMBL3628910 | 0.68 | BRD4 (0.46) | BRD4KDM4ELMNAALDH1A1PTGS2 | |
| SCHEMBL9163905 | 0.66 | BRD4 (0.56) | BRD4TSHR | |
| SCHEMBL15700133 | 0.63 | CYP19A1 (0.67) | CYP19A1HTR2CKDM4ELMNAPOLB | |
| SCHEMBL10583512 | 0.60 | LTA4H (0.48) | LMNAPOLBTSHRHTTALDH1A1 | |
| SCHEMBL5275161 | 0.60 | ACHE (0.73) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL9933801 | 0.60 | HTR1A (0.46) | HTR2CHTR2BUCHL1HCRTR1HCRTR2 | |
| SCHEMBL13518494 | 0.60 | HTR1A (0.46) | HTR2CHTR2BUCHL1HCRTR1HCRTR2 | |
| SCHEMBL3822324 | 0.60 | CYP19A1 (0.62) | CYP19A1KDM4ELMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408760-B1 | NEW HYDROXYLAMINE DERIVATIVE | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-03-15 | — | — | EP | disclosed |
| EP-0408760-A1 | NEW HYDROXYLAMINE DERIVATIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |