Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91749 | 0.83 | AR (0.35) | ARRAPGEF4PDK2 | |
| SCHEMBL91692 | 0.78 | AR (0.32) | ARRAPGEF4 | |
| SCHEMBL91801 | 0.74 | AR (0.35) | AR | |
| SCHEMBL29305754 | 0.71 | GRM5 (0.32) | — | |
| SCHEMBL18269958 | 0.70 | ALDH1A1 (0.38) | ARALDH1A1HPGD | |
| SCHEMBL7061834 | 0.70 | CES2 (0.42) | ARALDH1A1HPGD | |
| SCHEMBL28591458 | 0.70 | IDO1 (0.39) | ARALDH1A1HPGD | |
| SCHEMBL21386554 | 0.70 | ALDH1A1 (0.38) | ARALDH1A1HPGD | |
| SCHEMBL91700 | 0.69 | S1PR1 (0.43) | ARRAPGEF4AKR1C3AKR1C2PGR | |
| SCHEMBL3605338 | 0.69 | AR (0.41) | ARALDH1A1GLAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |