Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 11/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | RHOA | P61586 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | FOS | P01100 | 1/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9168215 | 1.00 | P4HB (0.56) | P4HBKDM4EALDH1A1SMN1; SMN2PKM | |
| SCHEMBL1225940 | 0.87 | P4HB (0.64) | P4HBNPSR1MAOAMAOB | |
| SCHEMBL30745014 | 0.87 | P4HB (0.64) | P4HBNPSR1MAOAMAOB | |
| SCHEMBL30912094 | 0.87 | P4HB (0.64) | P4HBNPSR1MAOAMAOB | |
| SCHEMBL1225943 | 0.87 | P4HB (0.64) | P4HBNPSR1MAOAMAOB | |
| Hydrochloric Acid SCHEMBL4101473 | 0.85 | P4HB (0.62) | P4HBNPSR1MAOAMAOB | |
| SCHEMBL1206897 | 0.84 | ALOX5 (0.68) | KDM4EALDH1A1SMN1; SMN2PKMALOX5 | |
| SCHEMBL30014477 | 0.84 | ALOX5 (0.68) | KDM4EALDH1A1SMN1; SMN2PKMALOX5 | |
| SCHEMBL1206895 | 0.84 | ALOX5 (0.68) | KDM4EALDH1A1SMN1; SMN2PKMALOX5 | |
| Hydrochloric Acid SCHEMBL11175049 | 0.82 | ALOX5 (0.67) | KDM4EALDH1A1SMN1; SMN2PKMALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649413-A1 | URACIL DERIVATIVES AS ENZYME INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-04-26 | — | — | EP | disclosed |
| WO-1994001414-A1 | URACIL DERIVATIVES AS ENZYME INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-01-20 | — | — | WO | disclosed |