Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9785123 | 0.90 | TET2 (0.43) | TET2TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL11289286 | 0.80 | CYP2C19 (0.52) | TET2TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL15074875 | 0.75 | TET2 (0.43) | TET2TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL10011850 | 0.73 | TET2 (0.64) | TET2TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL9077903 | 0.73 | MMP8 (0.42) | TSHRALDH1A1 | |
| SCHEMBL93137 | 0.72 | ALDH1A1 (0.38) | TET2TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL2345386 | 0.72 | TET2 (0.39) | TET2TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL16583132 | 0.72 | TSHR (0.38) | TET2TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL9579482 | 0.72 | TET2 (0.34) | TET2TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL25660671 | 0.71 | GGT1 (0.43) | TET2TSHRCYP2D6CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405427-B1 | Aromatic compounds, process for their preparation and their use as perfuming ingredients | FIRMENICH & CIE (CH) | 1995-03-29 | — | — | EP | disclosed |
| EP-0405427-A2 | Aromatic compounds, process for their preparation and their use as perfuming ingredients | FIRMENICH SA (CH) | 1991-01-02 | — | — | EP | disclosed |